I just checked the Etsy seller page. If you're asking whether the pearl is a natural as described, it's not. It's a Chinese freshwater pearl. All the "natural" pearl pieces are farmed Chinese freshwater pearls.
It's unfortunate because the seller is referencing astrological purposes and even offering one "natural certified South Sea" (it's not) in a setting that touches the skin.
These should be natural pearls or at the very least, untreated tissue-grafted pearls.
Maybe all the seller's natural rubies, emeralds and such a different. From the looks of it I doubt it. But from the pearl perspective, I would advise to steer clear of this seller.